Background:

This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Applications:

WB, IHC

Name of antibody:

CYCS

Immunogen:

Fusion protein of human CYCS

Full name:

cytochrome c, somatic

Synonyms:

CYC; HCS; THC4

SwissProt:

P99999

IHC positive control:

Human tonsil and Human thyroid cancer; Human ovarian cancer and Human esophagus cancer

IHC Recommend dilution:

100-500

WB Predicted band size:

12 kDa

WB Positive control:

Hela, 231, HepG2 and Jurkat cell, Mouse kidney tissue lysates

WB Recommended dilution:

5000-20000