Background:

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

Applications:

ELISA, IHC

Name of antibody:

WNT8B

Immunogen:

Synthetic peptide of humanWNT8B

Full name:

wingless-type MMTV integration site family, member 8B

SwissProt:

Q93098

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

10-50