Background:

This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

WDR83

Immunogen:

Fusion protein of human WDR83

Full name:

WD repeat domain 83

Synonyms：

MORG1

SwissProt:

Q9BRX9

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human colon cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

34 kDa

WB Positive control:

231 and A172 cells

WB Recommended dilution:

200-1000