Background:

The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

WDR77

Immunogen:

Fusion protein of human WDR77

Full name:

WD repeat domain 77

Synonyms:

p44; MEP50; MEP-50; HKMT1069; Nbla10071; p44/Mep50

SwissProt:

Q9BQA1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

100-300

WB Predicted band size:

37 kDa

WB Positive control:

LNCAP cell lysate

WB Recommended dilution:

500-2000