Background:

This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs.

Applications:

ELISA, WB, IHC

Name of antibody:

WRAP53

Immunogen:

Fusion protein of human WRAP53

Full name:

WD repeat containing, antisense to TP53

Synonyms：

DKCB3; TCAB1; WDR79

SwissProt:

Q9BUR4

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

59 kDa

WB Positive control:

HT-29, hela and A431 cell

WB Recommended dilution:

200-1000