Background:

This gene is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, WB

Name of antibody:

WHRN

Immunogen:

Synthetic peptide of human WHRN

Full name:

whirlin

Synonyms:

WI; CIP98; USH2D; DFNB31; PDZD7B

SwissProt:

Q9P202

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

97 kDa

WB Positive control:

293T, PC-3 and TM4 cell lysates

WB Recommended dilution:

200-1000